Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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U1_snRNA

SO:0000391

Definition: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

Comments and references

Definition references: http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00003

Synonyms

ScopeValue
exactU1 small nuclear RNA
exactU1 snRNA
exactsmall nuclear RNA U1
exactsnRNA U1

Identifiers and subsets

Accession: SO:0000391

Persistent URL: http://purl.obolibrary.org/obo/SO_0000391

Alternate IDs: None

Subsets: SOFA

Cross references: http://en.wikipedia.org/wiki/U1_snRNA

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2016-12-05 in commit 92e3cae

Number of changes: 1

Ontology neighborhood diagram

Ontology neighborhood for SO:0000391 Ontology neighborhood graph for SO:0000391 U1_snRNA. Parent, child, and related nodes can be activated to open their term pages. SO:0000274 snRNA SO:0000274 snRNA SO:0000391 U1_snRNA SO:0000391 U1_snRNA
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

None recorded in the current release neighborhood.

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2016-12-05createdTerm introduced into the editable ontology history
Initial label: U1_snRNA
Initial definition captured.
Initial parent: SO:0000274
92e3cae