U4_snRNA (CURRENT_RELEASE) |
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| SO Accession: | SO:0000393 (SOWiki) |
| Definition: | U4 small nuclear RNA (U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to refold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6. |
| Synonyms: | small nuclear RNA U4, snRNA U4, U4 small nuclear RNA, U4 snRNA |
| DB Xrefs: | URL: http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015 |
| Parent: | snRNA (SO:0000274) |
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