Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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frameshift_variant

SO:0001589

Definition: A sequence variant which causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three.

Comments and references

EBI term:Frameshift variations - In coding sequence, resulting in a frameshift.

Definition references: SO:ke

Synonyms

ScopeValue
exactJannovar:frameshift_variant
exactSeattleseq:frameshift
exactVAAST:frameshift_variant
exactVEP:frameshift_variant
exactframeshift variant
exactframeshift_
exactframeshift_coding
exactsnpEff:FRAME_SHIFT
relatedANNOVAR:frameshift block substitution
relatedANNOVAR:frameshift substitution
relatedSeattleseq:frameshift-near-splice
narrowVAT:deletionFS
narrowVAT:insertionFS

Identifiers and subsets

Accession: SO:0001589

Persistent URL: http://purl.obolibrary.org/obo/SO_0001589

Alternate IDs: None

Subsets: None

Cross references: http://snp.gs.washington.edu/SeattleSeqAnnotation137/HelpHowToUse.jsp, http://snpeff.sourceforge.net/SnpEff_manual.html, http://vat.gersteinlab.org/formats.php, http:www.ensembl.org/info/genome/variation/predicted_data.html#consequences, loinc:LA6694-9

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2016-12-05 in commit 92e3cae

Number of changes: 1

Ontology neighborhood diagram

Ontology neighborhood for SO:0001589 Ontology neighborhood graph for SO:0001589 frameshift_variant. Parent, child, and related nodes can be activated to open their term pages. SO:0001818 protein_altering_variant SO:0001818 protein_altering_variant SO:0001589 frameshift_variant SO:0001589 frameshift_variant SO:0001910 frameshift_truncation SO:0001910 frameshift_truncation SO:0001595 plus_2_frameshift_variant SO:0001595 plus_2_frameshift_variant SO:0001593 minus_2_frameshift_variant SO:0001593 minus_2_frameshift_variant SO:0001594 plus_1_frameshift_variant SO:0001594 plus_1_frameshift_variant SO:0001591 frame_restoring_variant SO:0001591 frame_restoring_variant SO:0001592 minus_1_frameshift_variant SO:0001592 minus_1_frameshift_variant
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2016-12-05createdTerm introduced into the editable ontology history
Initial label: frameshift_variant
Initial definition captured.
Initial parent: SO:0001818
92e3cae