destruction_box (CURRENT_SVN) |
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SO Accession: | SO:0001805 (SOWiki) |
Definition: | A conserved polypeptide motif that can be recognized by both Fizzy/Cdc20- and FZR/Cdh1-activated anaphase-promoting complex/cyclosome (APC/C) and targets a protein for ubiquitination and subsequent degradation by the APC/C. The consensus sequence is RXXLXXXXN. |
Synonyms: | D-box, destruction box |
DB Xrefs: | PMID: 12208841 |
PMID: 1842691 | |
Parent: | polypeptide_conserved_motif (SO:0100017) |
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