C_D_box_snoRNA_gene (CURRENT_SVN) |
|
|---|---|
| SO Accession: | SO:0002375 (SOWiki) |
| Definition: | A gene that codes a C_D_box_snoRNA. Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'. |
| Synonyms: | box C/D snoRNA gene, C D box snoRNA gene, C/D box snoRNA gene |
| DB Xrefs: | PMID: 12457565 |
| PMID: 22065625 | |
| Parent: | snoRNA_gene (SO:0001267) |
| Children: | U14_snoRNA_gene (SO:0002377) |
| methylation_guide_snoRNA_gene (SO:0002379) | |
| U3_snoRNA_gene (SO:0002378) | |
In the image below graph nodes link to the appropriate terms. Clicking the image background will toggle the image between large and small formats.
