destruction_box (RELEASE_2.5.1) |
|
|---|---|
| SO Accession: | SO:0001805 (SOWiki) |
| Definition: | A conserved polypeptide motif that can be recognized by both Fizzy/Cdc20- and FZR/Cdh1-activated anaphase-promoting complex/cyclosome (APC/C) and targets a protein for ubiquitination and subsequent degradation by the APC/C. The consensus sequence is RXXLXXXXN. |
| Synonyms: | D-box, destruction box |
| DB Xrefs: | PMID: 12208841 |
| PMID: 1842691 | |
| Parent: | polypeptide_conserved_motif (SO:0100017) |
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