tRNA (CURRENT_RELEASE) |
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SO Accession: | SO:0000253 (SOWiki) |
Definition: | Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. |
Synonyms: | transfer ribonucleic acid, transfer RNA, INSDC_feature:tRNA, INSDC_qualifier:unknown |
DB Xrefs: | URL: http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00005 |
ISBN: 0198506732 | |
Parents: | sncRNA (SO:0002247) |
tRNA_primary_transcript (SO:0000210) | |
Children: | alanyl_tRNA (SO:0000254) |
glutaminyl_tRNA (SO:0000259) | |
prolyl_tRNA (SO:0000268) | |
glutamyl_tRNA (SO:0000260) | |
methionyl_tRNA (SO:0000266) | |
asparaginyl_tRNA (SO:0000256) | |
threonyl_tRNA (SO:0000270) | |
glycyl_tRNA (SO:0000261) | |
valyl_tRNA (SO:0000273) | |
tyrosyl_tRNA (SO:0000272) | |
cysteinyl_tRNA (SO:0000258) | |
isoleucyl_tRNA (SO:0000263) | |
seryl_tRNA (SO:0000269) | |
leucyl_tRNA (SO:0000264) | |
tryptophanyl_tRNA (SO:0000271) | |
selenocysteinyl_tRNA (SO:0005857) | |
pyrrolysyl_tRNA (SO:0000766) | |
lysyl_tRNA (SO:0000265) | |
aspartyl_tRNA (SO:0000257) | |
arginyl_tRNA (SO:0001036) | |
histidyl_tRNA (SO:0000262) | |
tRNA_region (SO:0001172) | |
mt_tRNA (SO:0002129) | |
phenylalanyl_tRNA (SO:0000267) |
In the image below graph nodes link to the appropriate terms. Clicking the image background will toggle the image between large and small formats.
![Graph image for SO:0000253](http://sequenceontology.org/img/dag_gif/current_release/SO:0000253_sm.png)