L1_LINE_retrotransposon (CURRENT_RELEASE) |
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|---|---|
| SO Accession: | SO:0002272 (SOWiki) |
| Definition: | Long interspersed element-1 (LINE-1) elements are found in the human genome, which contains ORF1 (open reading frame1, including CC, coiled coil; RRM, RNA recognition motif; CTD, carboxyl-terminal domain) and ORF2 (including EN, endonuclease; RT, reverse transcriptase; C, cysteine-rich domain). The L1-encoded proteins (ORF1p and ORF2p) can mobilize nonautonomous retrotransposons, other noncoding RNAs, and messenger RNAs. |
| Synonyms: | L1 element, L1 LINE retrotransposon, LINE 1 element, LINE-1 element |
| DB Xrefs: | PMID: 31709017 |
| Parent: | LINE_element (SO:0000194) |
| Children: | LINE1_deletion (SO:0002069) |
| LINE1_insertion (SO:0002064) | |
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