locus_control_region
SO:0000037
Definition: A DNA region that includes DNAse hypersensitive sites located near a gene that confers the high-level, position-independent, and copy number-dependent expression to that gene.
Comments and references
Definition updated Nov 10 2020, Colin Logie from GREEKC helped us realize that LCRs can also be located 3' to a gene.
Definition references: SO:ma
Synonyms
| Scope | Value |
|---|---|
| exact | INSDC_qualifier:locus_control_region |
| exact | LCR |
| exact | locus control region |
| related | locus control element |
| broad | INSDC_feature:regulatory |
Identifiers and subsets
Accession: SO:0000037
Persistent URL: http://purl.obolibrary.org/obo/SO_0000037
Alternate IDs: None
Subsets: None
Cross references: http://en.wikipedia.org/wiki/Locus_control_region
History summary
Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.
First seen in Git-era editable history: 2016-12-05 in commit 92e3cae
Most recent Git-era change: 2021-02-08 in commit 9fa74b8
Number of changes: 5
Ontology neighborhood diagram
Relationships
Parents
Children
None recorded in the current release neighborhood.
Change history
This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.
| Date | Change | Summary | Evidence |
|---|---|---|---|
| 2021-02-08 | edited | Term stanza touched in repository history | 9fa74b8#526 |
| 2020-11-10 | definition changed | Definition updated Before: A DNA region that includes DNAse hypersensitive sites located 5' to a gene that confers the high-level, position-independent, and copy number-dependent expression to that gene. After: A DNA region that includes DNAse hypersensitive sites located near a gene that confers the high-level, position-independent, and copy number-dependent expression to that gene. | c421726 |
| 2018-01-26 | synonym added | Synonym added: INSDC_qualifier:locus_control_region Scope: exact | 5fe48bd |
| 2018-01-26 | synonym added | Synonym added: INSDC_feature:regulatory Scope: broad | 5fe48bd |
| 2016-12-05 | created | Term introduced into the editable ontology history Initial label: locus_control_region Initial definition captured. Initial parent: SO:0000727 | 92e3cae |