Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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stop_codon

SO:0000319

Definition: In mRNA, a set of three nucleotides that indicates the end of information for protein synthesis. In genomic sequence, a stop codon may be only one or two nucleotides where the additional nucleotides are provided in the RNA via polyadenylation.

Comments and references

Definition references: SO:ke

Synonyms

ScopeValue
exactstop codon

Identifiers and subsets

Accession: SO:0000319

Persistent URL: http://purl.obolibrary.org/obo/SO_0000319

Alternate IDs: None

Subsets: SOFA

Cross references: http://en.wikipedia.org/wiki/Stop_codon

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2025-09-09 in commit 993ca33

Number of changes: 2

Ontology neighborhood diagram

Ontology neighborhood for SO:0000319 Ontology neighborhood graph for SO:0000319 stop_codon. Parent, child, and related nodes can be activated to open their term pages. SO:0000360 codon SO:0000360 codon SO:0000319 stop_codon SO:0000319 stop_codon SO:0002333 amber_stop_codon SO:0002333 amber_stop_codon SO:0002334 ochre_stop_codon SO:0002334 ochre_stop_codon SO:0002335 opal_stop_codon SO:0002335 opal_stop_codon
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2025-09-09definition changedDefinition updated
Before: In mRNA, a set of three nucleotides that indicates the end of information for protein synthesis.
After: In mRNA, a set of three nucleotides that indicates the end of information for protein synthesis. In genomic sequence, a stop codon may be only one or two nucleotides where the additional nucleotides are provided in the RNA via polyadenylation.
993ca33
2016-12-05createdTerm introduced into the editable ontology history
Initial label: stop_codon
Initial definition captured.
Initial parent: SO:0000360
92e3cae