Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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signal_peptide

SO:0000418

Definition: The signal_peptide is a short region of the peptide located at the N-terminus that directs the protein to be secreted or part of membrane components.

Comments and references

Old def before biosapiens:The sequence for an N-terminal domain of a secreted protein; this domain is involved in attaching nascent polypeptide to the membrane leader sequence.

Definition references: http://www.insdc.org/files/feature_table.html

Synonyms

ScopeValue
exactINSDC_feature:sig_peptide
exactsignal peptide
exactsignal peptide coding sequence
relatedsignal

Identifiers and subsets

Accession: SO:0000418

Persistent URL: http://purl.obolibrary.org/obo/SO_0000418

Alternate IDs: BS:00159

Subsets: SOFA, biosapiens

Cross references: http://en.wikipedia.org/wiki/Signal_peptide

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2020-07-01 in commit 2e01a41

Number of changes: 5

Ontology neighborhood diagram

Ontology neighborhood for SO:0000418 Ontology neighborhood graph for SO:0000418 signal_peptide. Parent, child, and related nodes can be activated to open their term pages. SO:0001527 peptide_localization_signal SO:0001527 peptide_localization_signal SO:0000418 signal_peptide SO:0000418 signal_peptide SO:0001809 signal_anchor SO:0001809 signal_anchor SO:0002251 signal_peptide_region_of_CDS SO:0002251 signal_peptide_region_of_CDS SO:0001062 propeptide SO:0001062 propeptide SO:0100016 central_hydrophobic_region_of_signal_peptide SO:0100016 central_hydrophobic_region_of_signal_peptide SO:0100015 c_terminal_region SO:0100015 c_terminal_region
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

http://purl.obolibrary.org/obo/so#derives_from (outgoing)

http://purl.obolibrary.org/obo/so#part_of (outgoing)

http://purl.obolibrary.org/obo/so#part_of (incoming)

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2020-07-01editedTerm stanza touched in repository history2e01a41
2020-05-27editedTerm stanza touched in repository historyb13f9f0
2020-05-13editedTerm stanza touched in repository history74ff3d6
#484
2018-01-26synonym addedSynonym added: INSDC_feature:sig_peptide
Scope: exact
5fe48bd
2016-12-05createdTerm introduced into the editable ontology history
Initial label: signal_peptide
Initial definition captured.
Initial parent: SO:0001527
92e3cae