SO:0002010 - pyrrolysine

pyrrolysine_loss

SO:0002010

Definition: A sequence variant whereby at least one base of a codon encoding pyrrolysine is changed, resulting in a different encoded amino acid.

Comments and references

Request from Uma Devi Paila, UVA. Variants in the sites of rare amino acids e.g. Selenocysteine. These are important impact terms since a loss of such rare amino acids may lead to a loss of function.

Definition references: SO:ke

Synonyms

Scope	Value
exact	pyrrolysine loss

Identifiers and subsets

Accession: SO:0002010

Persistent URL: http://purl.obolibrary.org/obo/SO_0002010

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2021-07-12 in commit 795c410

Number of changes: 2

Ontology neighborhood diagram

The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

SO:0002008 - rare_amino_acid_variant

Children

None recorded in the current release neighborhood.

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

Date	Change	Summary	Evidence
2021-07-12	edited	Term stanza touched in repository history	`795c410`
2016-12-05	created	Term introduced into the editable ontology history Initial label: pyrrolysine_loss Initial definition captured. Initial parent: SO:0002008	`92e3cae`