SO:0000014 - INR

INR_motif

SO:0000014

Definition: A sequence element characteristic of some RNA polymerase II promoters required for the correct positioning of the polymerase for the start of transcription. Overlaps the TSS. The mammalian consensus sequence is YYAN(T|A)YY; the Drosophila consensus sequence is TCA(G|T)t(T|C). In each the A is at position +1 with respect to the TSS. Functionally similar to the TATA box element.

Comments and references

Binds TAF1, TAF2.

Definition references: PMID:12651739, PMID:16858867

Synonyms

Scope	Value
exact	INR motif
exact	initiator
exact	initiator motif
related	DMp2

Identifiers and subsets

Accession: SO:0000014

Persistent URL: http://purl.obolibrary.org/obo/SO_0000014

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2019-07-31 in commit ad4ec85

Number of changes: 2

Ontology neighborhood diagram

The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

SO:0001660 - core_eukaryotic_promoter_element

Children

None recorded in the current release neighborhood.

http://purl.obolibrary.org/obo/so#part_of (outgoing)

SO:0001669 - RNApol_II_core_promoter

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

Date	Change	Summary	Evidence
2019-07-31	edited	Term stanza touched in repository history	`ad4ec85`
2016-12-05	created	Term introduced into the editable ontology history Initial label: INR_motif Initial definition captured. Initial parent: SO:0001660	`92e3cae`