DPE_motif

SO:0000015

Definition: A sequence element characteristic of some RNA polymerase II promoters; Positioned from +28 to +32 with respect to the TSS (+1). Experimental results suggest that the DPE acts in conjunction with the INR_motif to provide a binding site for TFIID in the absence of a TATA box to mediate transcription of TATA-less promoters. Consensus sequence (A|G)G(A|T)(C|T)(G|A|C).

Comments and references

Binds TAF6, TAF9.

Definition references: PMID:12515390, PMID:12537576, PMID:12651739, PMID:16858867

Synonyms

ScopeValue
exactDPE motif
exactdownstream core promoter element
narrowCRWMGCGWKCGCTTS

Identifiers and subsets

Accession: SO:0000015

Persistent URL: http://purl.obolibrary.org/obo/SO_0000015

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2020-08-13 in commit a1a7db8

Number of changes: 3

Ontology neighborhood diagram

Ontology neighborhood for SO:0000015 Ontology neighborhood graph for SO:0000015 DPE_motif. Parent, child, and related nodes can be activated to open their term pages. SO:0001660 core_eukaryotic_promoter_element SO:0001660 core_eukaryotic_promoter_element SO:0000015 DPE_motif SO:0000015 DPE_motif SO:0001669 RNApol_II_core_promoter SO:0001669 RNApol_II_core_promoter
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

None recorded in the current release neighborhood.

http://purl.obolibrary.org/obo/so#part_of (outgoing)

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2020-08-13editedTerm stanza touched in repository historya1a7db8
2019-07-31editedTerm stanza touched in repository historyad4ec85
2016-12-05createdTerm introduced into the editable ontology history
Initial label: DPE_motif
Initial definition captured.
Initial parent: SO:0001660
92e3cae