Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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SECIS_element

SO:1001274

Definition: The incorporation of selenocysteine into a protein sequence is directed by an in-frame UGA codon (usually a stop codon) within the coding region of the mRNA. Selenoprotein mRNAs contain a conserved secondary structure in the 3' UTR that is required for the distinction of UGA stop from UGA selenocysteine. The selenocysteine insertion sequence (SECIS) is around 60 nt in length and adopts a hairpin structure which is sufficiently well-defined and conserved to act as a computational screen for selenoprotein genes.

Comments and references

Definition references: http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00031

Synonyms

ScopeValue
exactSECIS element

Identifiers and subsets

Accession: SO:1001274

Persistent URL: http://purl.obolibrary.org/obo/SO_1001274

Alternate IDs: None

Subsets: None

Cross references: http://en.wikipedia.org/wiki/SECIS_element

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2016-12-05 in commit 92e3cae

Number of changes: 1

Ontology neighborhood diagram

Ontology neighborhood for SO:1001274 Ontology neighborhood graph for SO:1001274 SECIS_element. Parent, child, and related nodes can be activated to open their term pages. SO:1001268 recoding_stimulatory_region SO:1001268 recoding_stimulatory_region SO:1001274 SECIS_element SO:1001274 SECIS_element
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

None recorded in the current release neighborhood.

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2016-12-05createdTerm introduced into the editable ontology history
Initial label: SECIS_element
Initial definition captured.
Initial parent: SO:1001268
92e3cae